Again, you're not taking out JRP after the first INT, not even the genius' on this board would ask for that. But let's say we listen to the board and take him out after the fumble. (which was never going to happen) After that fumble JRP 22/32 for 262 yards, an INT that was on 4th down so incomplete would've had the same result, and then a desperation INT in the final seconds of a blowout game. Those aren't exactly terrible numbers.
So again, my question is, if anything would've changed if Castellanos would've been brought into the game? Those first 2 turnovers by JRP were absolute killers, there's no doubt about that, he's got to do better, but the premise of this thread is that Castellanos being brought into the game after those turnovers would somehow have changed something and it's easy to see that it wouldn't have mattered unless Castellanos somehow figured out how to scheme and implement a defense while also performing his QB duties.